An in silico ADMET, molecular docking study and microwave-assisted synthesis of new phosphorylated derivatives of thiazolidinedione as potential anti-diabetic agents

An in silico ADMET, molecular docking study and microwave-assisted synthesis of new phosphorylated derivatives of thiazolidinedione as potential anti-diabetic agents

A series of new phosphorylated derivatives of thiazolidinedione was synthesized for the first time with high yields (92–96%) in short reaction time (7–15min) by the reaction of 4-{[(5E)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl ethyl phosphorochloridate with various heterocyclic amines by mi...

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Bibliographic Details
Main Authors: Hanumantha Rao Addanki, Madhava Rao Vallabhaneni, Subramanyam Chennamsett, Priyadarshini Pullagura, Someswara Rao Sagurthi, Pasupuleti Visweswara Rao
Format: Article
Language:English
English
Published: Taylor and Francis 2022
Subjects:
RC31-1245 Internal medicine
Online Access:https://eprints.ums.edu.my/id/eprint/28949/1/An%20in%20silico%20ADMET%2C%20molecular%20docking%20study%20and%20microwave-assisted%20synthesis%20of%20new%20phosphorylated%20derivatives%20of%20thiazolidinedione%20as%20potential%20anti-diabetic%20agents.pdf
https://eprints.ums.edu.my/id/eprint/28949/2/An%20in%20silico%20ADMET%2C%20molecular%20docking%20study%20and%20microwave-assisted%20synthesis%20of%20new%20phosphorylated%20derivatives%20of%20thiazolidinedione%20as%20potential%20anti-diabetic%20agents%20_ABSTRACT.pdf

Internet

https://eprints.ums.edu.my/id/eprint/28949/1/An%20in%20silico%20ADMET%2C%20molecular%20docking%20study%20and%20microwave-assisted%20synthesis%20of%20new%20phosphorylated%20derivatives%20of%20thiazolidinedione%20as%20potential%20anti-diabetic%20agents.pdf
https://eprints.ums.edu.my/id/eprint/28949/2/An%20in%20silico%20ADMET%2C%20molecular%20docking%20study%20and%20microwave-assisted%20synthesis%20of%20new%20phosphorylated%20derivatives%20of%20thiazolidinedione%20as%20potential%20anti-diabetic%20agents%20_ABSTRACT.pdf

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