Association of endothelin-converting enzyme and endothelin-1 gene polymorphisms with essential hypertension in Malay ethnics
Objectives. Endothelin-1 (ET-1), the most potent endogenous vasoconstrictor, generated by enzymatic cleavage catalyzed by an endothelin-converting enzyme (ECE), plays a significant role in the regulation of hypertension. Methods. This study investigates the effect of endothelin-1 (Lys198Asn/rs5370)...
| Main Authors: | , , , , , , |
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| Format: | Article |
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Cambridge University Press
2022
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