Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2
Loss of function of the neurofibromatosis type 2 (NF2) tumor suppressor gene leads to the formation of schwannomas, meningiomas, and ependymomas, comprising ∼50% of all sporadic cases of primary nervous system tumors. NF2 syndrome is an autosomal dominant condition, with bi-allelic inactivation of g...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Cell Press
2022
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