Probing the substrate binding modes and catalytic mechanisms of bleg-1, a promiscuous b3 metallo-β-lactamase with glyoxalase ii properties
BLEG-1 from <jats:italic>Bacillus lehensis</jats:italic> G1 is an evolutionary divergent B3 metallo-β-lactamase (MBL) that exhibited both β-lactamase and glyoxalase II (GLXII) activities. Sequence, phylogeny, biochemical and structural relatedness of BLEG-1 to B3 MBL and...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science
2023
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Online Access: | http://psasir.upm.edu.my/id/eprint/110023/1/journal.pone.0291012.pdf |