Itraconazole and fluconazole-induced toxicity in rat hepatocytes: a comparativein vitro study

This current study was to investigate the in vitrocytotoxicity of rat hepatocytes induced by the antifungal drugs, itraconazole and fluconazole. Both antifungal drugs caused dose-dependent cytotoxicity. In vitro incubation of hepatocytes with itraconazole revealed significantly higher lactate dehydr...

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Bibliographic Details
Main Authors: Somchit, N, Hassim, SM, Samsudin, SH
Format: Article
Language:English
Published: SAGE Publications 2002
Online Access:http://psasir.upm.edu.my/id/eprint/112712/1/112712.pdf