Enhanced interferon-α2b production in periplasmic space of Escherichia coli through medium optimization using response surface method
The influence of different carbon and nitrogen sources on growth of recombinant Escherichia coli and human interferon-α2b (IFN-α2b) production in periplasmic space was studied in shake flask culture. A statistical method based on Plackett-Burman design was used to screen the main medium components t...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bentham Open
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/14509/1/Enhanced%20interferon-%CE%B12b%20production%20in%20periplasmic%20space%20of%20Escherichia%20coli%20through%20medium%20optimization%20using%20response%20surface%20method.pdf |