Enhancement of monoclonal antibody productivity by promoting active hypothermic growth in hybridoma cells
BACKGROUND: Many reports have suggested that mild hypothermic culture conditions improve the specific monoclonal antibody (mAb) productivity of mammalian cells. The effect of active hypothermic growth on the mAb productivity of the hybridoma C2E7 was investigated. Hybridoma growth under hypothermic...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Society of Chemical Industry
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/14517/1/Enhancement%20of%20monoclonal%20antibody%20productivity%20by%20promoting%20active%20hypothermic%20growth%20in%20hybridoma%20cells.pdf |