Molecular responses during chemotherapy in acute myeloid leukemias in predicting poor-response to standard chemotherapy.
Signal transduction pathways are constitutively expressed in leukaemic cells resulting in aberrant survival of the cells. It is postulated that in cells of chemo-sensitive patients, chemotherapy induces apoptotic signals leading to cell death while survival signals are maintained in cells of chemore...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Malaysian Society of Pathologists
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/15713/1/Molecular%20responses%20during%20chemotherapy%20in%20acute%20myeloid%20leukemias%20in%20predicting%20poor.pdf |