Toxicity evaluation of dextran-spermine polycation as a tool for genetherapy in vitro.

Cationic polymers are a leading class of nonviral self-assembled nucleic acid delivery systems. Cationic polymers have been shown to condence the DNA so that the entrapped DNA is protected from contact with DNase. The objective of the present study is to evaluate the effect of cationic dextran on th...

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Bibliographic Details
Main Authors: Abedini, Fatemah, Ismail, Maznah, Hosseinkhani, Hossein, Tengku Ibrahim, Tengku Azmi, Omar, Abdolrahman, Chong, Pei Pei, Ismail, Norsharina, Farber, Ira-Yudovin, Domb, Abraham J.
Format: Article
Language:English
English
Published: Academic Journals 2010
Online Access:http://psasir.upm.edu.my/id/eprint/17451/1/Toxicity%20evaluation%20of%20dextran.pdf