Vehicle or placebo? Investigators use incorrect terminology in randomized controlled trials half of the time: A systematic review of randomized controlled trials published in three major dermatology journals.

Background: A topical comparison in a randomized controlled trial (RCT) should correctly be termed a vehicle rather than a placebo as the vehicle in a dermatologic drug product enhances delivery and efficacy of the active compound. Objectives: To conduct a systematic review of RCTs involving...

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Bibliographic Details
Main Authors: Shamsudin, Shamsudin, Fleischer, Alan B.
Format: Article
Published: Strategic Communication in Dermatology 2010
Subjects: