Delivery of chimeric hepatitis B core particles into liver cells.
AIMS: To display a liver-specific ligand on the hepatitis B virus core particles for cell-targeting delivery. METHODS AND RESULTS: A liver cell-binding ligand (preS1) was fused at the N-terminal end of the hepatitis B core antigen (HBcAg), but the fusion protein (preS1His(6) HBcAg) was insolu...
Main Authors: | , , , |
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Format: | Article |
Language: | English English |
Published: |
2012
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Online Access: | http://psasir.upm.edu.my/id/eprint/23439/1/Delivery%20of%20chimeric%20hepatitis%20B%20core%20particles%20into%20liver%20cells.pdf |