Improved in vitro development of cloned bovine embryos using S-Adenosylhomocysteine, a non-toxic epigenetic modifying reagent.
In this study, fibroblast cells were stably transfected with mouse POU5F1 promoter-driven enhanced green fluorescent protein (EGFP) to investigate the effect of S-adenosylhomocysteine (SAH), the reversible non-toxic inhibitor of DNA-methyltransferases (DNMTs), at different intervals post-fusion on i...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English English |
Published: |
Wiley-Blackwell
2011
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Online Access: | http://psasir.upm.edu.my/id/eprint/23827/1/Improved%20in%20vitro%20development%20of%20cloned%20bovine%20embryos%20using%20S.pdf |