Variant toll-like receptor4 (Asp299Gly and Thr399Ile alleles) and toll-like receptor2 (Arg753Gln and Arg677Trp alleles) in colorectal cancer.
The innate immune system recognizes the presence of bacterial products through the expression of a family of membrane receptors known as Toll-like receptors (TLRs). Polymorphisms in TLRs have been shown to be associated with increased susceptibility to diseases such as inflammatory bowel disease. Th...
Main Authors: | , |
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Format: | Article |
Language: | English English |
Published: |
Tehran University of Medical Sciences
2011
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Online Access: | http://psasir.upm.edu.my/id/eprint/24499/1/Variant%20toll.pdf |