Engineering an L-cell line that expresses insulin under the control of the glucagon-like peptide-1 promoter for diabetes treatment

Background: Diabetes mellitus is a complicated disease with a pathophysiology that includes hyperinsulinemia, hyperglycemia and other metabolic impairments leading to many clinical complications. It is necessary to develop appropriate treatments to manage the disease and reduce possible acute and ch...

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Bibliographic Details
Main Authors: Rasouli, Mina, Ahmad, Zalinah, Omar, Abdul Rahman, Allaudin, Zeenathul Nazariah
Format: Article
Language:English
Published: BioMed Central 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24523/1/24523.pdf