Zerumbone-induced antinociception: involvement of the L-arginine-nitric oxide-cGMP -PKC-K+ ATP channel pathways.

This study investigated the antinociceptive effects of zerumbone in chemical behavioural models of nociception in mice. Zerumbone given through intraperitoneal route (i.p.) produced dose-related antinociception when assessed on acetic acid-induced abdominal writhing test in mice. In addition, the i...

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Bibliographic Details
Main Authors: Perimal, Enoch Kumar, Akhtar, Muhammad Nadeem, Tengku Mohamad, Tengku Azam Shah, Khalid, Mohamed Hanief, Ong, Hui Ming, Khalid, Syamimi, Lee, Ming Tatt, Kamaldin, Mohd Nasier, Zakaria, Zainul Amiruddin, Israf Ali, Daud Ahmad, Lajis, Md. Nordin, Sulaiman, Mohd Roslan
Format: Article
Language:English
Published: Wiley 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24554/1/Zerumbone.pdf