Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.
The dengue virus is the most significant arthropod-borne human pathogen, and an increasing number of cases have been reported over the last few decades. Currently neither vaccines nor drugs against the dengue virus are available. NS5 methyltransferase (MTase), which is located on the surface of the...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English English |
Published: |
BioMed Central
2011
|
Online Access: | http://psasir.upm.edu.my/id/eprint/25113/1/Structure-based%20and%20ligand-based%20virtual%20screening%20of%20novel%20methyltransferase%20inhibitors%20of%20the%20dengue%20virus..pdf |