Downregulation of RhoGDIα increased migration and invasion of ER+ MCF7 and ER− MDA-MB-231 breast cancer cells.

Downregulation of RhoGDIα increased migration and invasion of ER+ MCF7 and ER− MDA-MB-231 breast cancer cells.

Rho GDp dissociation inhibitors (RhoGDIs) can inhibit cell motility, invasion, and metastasis in cancer by inactivating the RhoGTpases. A member of RhoGDI family has been consistently shown to interact with estrogen receptor (eR), and change its transcriptional activity. eR is a receptor known t...

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Bibliographic Details
Main Authors: Hooshmand, Somayeh, Ghaderi, Abbas, Yusoff, Khatijah, Karrupiah, Thilakavathy, Rosli, Rozita, Mojtahedi, Zahra
Format: Article
Language:English
English
Published: Landes Bioscience 2013
Online Access:http://psasir.upm.edu.my/id/eprint/28133/1/Downregulation%20of%20RhoGDI%CE%B1%20increased%20migration%20and%20invasion%20of%20ER.pdf

Internet

http://psasir.upm.edu.my/id/eprint/28133/1/Downregulation%20of%20RhoGDI%CE%B1%20increased%20migration%20and%20invasion%20of%20ER.pdf

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