Cruciferous vegetables: dietary phytochemicals for cancer prevention
Relationships between diet and health have attracted attention for centuries; but links between diet and cancer have been a focus only in recent decades. The consumption of diet-containing carcinogens, including polycyclic aromatic hydrocarbons and heterocyclic amines is most closely correlated with...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Asian Pacific Organization for Cancer Prevention
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29604/1/Cruciferous%20vegetables.pdf |
| _version_ | 1825947544094507008 |
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| author | Abdull Razis, Ahmad Faizal Mohd Noor, Noramaliza |
| author_facet | Abdull Razis, Ahmad Faizal Mohd Noor, Noramaliza |
| author_sort | Abdull Razis, Ahmad Faizal |
| collection | UPM |
| description | Relationships between diet and health have attracted attention for centuries; but links between diet and cancer have been a focus only in recent decades. The consumption of diet-containing carcinogens, including polycyclic aromatic hydrocarbons and heterocyclic amines is most closely correlated with increasing cancer risk. Epidemiological evidence strongly suggests that consumption of dietary phytochemicals found in vegetables and fruit can decrease cancer incidence. Among the various vegetables, broccoli and other cruciferous species appear most closely associated with reduced cancer risk in organs such as the colorectum, lung, prostate and breast. The protecting effects against cancer risk have been attributed, at least partly, due to their comparatively high amounts of glucosinolates, which differentiate them from other vegetables. Glucosinolates, a class of sulphur- containing glycosides, present at substantial amounts in cruciferous vegetables, and their breakdown products such as the isothiocyanates, are believed to be responsible for their health benefits. However, the underlying mechanisms responsible for the chemopreventive effect of these compounds are likely to be manifold, possibly concerning very complex interactions, and thus difficult to fully understand. Therefore, this article provides a brief overview about the mechanism of such compounds involved in modulation of carcinogen metabolising enzyme systems. |
| first_indexed | 2024-03-06T08:15:00Z |
| format | Article |
| id | upm.eprints-29604 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:15:00Z |
| publishDate | 2013 |
| publisher | Asian Pacific Organization for Cancer Prevention |
| record_format | dspace |
| spelling | upm.eprints-296042015-09-09T01:42:01Z http://psasir.upm.edu.my/id/eprint/29604/ Cruciferous vegetables: dietary phytochemicals for cancer prevention Abdull Razis, Ahmad Faizal Mohd Noor, Noramaliza Relationships between diet and health have attracted attention for centuries; but links between diet and cancer have been a focus only in recent decades. The consumption of diet-containing carcinogens, including polycyclic aromatic hydrocarbons and heterocyclic amines is most closely correlated with increasing cancer risk. Epidemiological evidence strongly suggests that consumption of dietary phytochemicals found in vegetables and fruit can decrease cancer incidence. Among the various vegetables, broccoli and other cruciferous species appear most closely associated with reduced cancer risk in organs such as the colorectum, lung, prostate and breast. The protecting effects against cancer risk have been attributed, at least partly, due to their comparatively high amounts of glucosinolates, which differentiate them from other vegetables. Glucosinolates, a class of sulphur- containing glycosides, present at substantial amounts in cruciferous vegetables, and their breakdown products such as the isothiocyanates, are believed to be responsible for their health benefits. However, the underlying mechanisms responsible for the chemopreventive effect of these compounds are likely to be manifold, possibly concerning very complex interactions, and thus difficult to fully understand. Therefore, this article provides a brief overview about the mechanism of such compounds involved in modulation of carcinogen metabolising enzyme systems. Asian Pacific Organization for Cancer Prevention 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29604/1/Cruciferous%20vegetables.pdf Abdull Razis, Ahmad Faizal and Mohd Noor, Noramaliza (2013) Cruciferous vegetables: dietary phytochemicals for cancer prevention. Asian Pacific Journal of Cancer Prevention, 14 (3). pp. 1565-1570. ISSN 1513-7368 http://www.apocpcontrol.org/page/apjcp_issues_view.php?pno=4256&gubun=p&s_search=&s_paper_vol=14&s_number33=3 10.7314/APJCP.2013.14.3.1565 |
| spellingShingle | Abdull Razis, Ahmad Faizal Mohd Noor, Noramaliza Cruciferous vegetables: dietary phytochemicals for cancer prevention |
| title | Cruciferous vegetables: dietary phytochemicals for cancer prevention |
| title_full | Cruciferous vegetables: dietary phytochemicals for cancer prevention |
| title_fullStr | Cruciferous vegetables: dietary phytochemicals for cancer prevention |
| title_full_unstemmed | Cruciferous vegetables: dietary phytochemicals for cancer prevention |
| title_short | Cruciferous vegetables: dietary phytochemicals for cancer prevention |
| title_sort | cruciferous vegetables dietary phytochemicals for cancer prevention |
| url | http://psasir.upm.edu.my/id/eprint/29604/1/Cruciferous%20vegetables.pdf |
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