Mechanistic basis for protection of differentiated SH-SY5Y cells by oryzanol-rich fraction against hydrogen peroxide-induced neurotoxicity

Background Apoptosis is often the end result of oxidative damage to neurons. Due to shared pathways between oxidative stress, apoptosis and antioxidant defence systems, an oxidative insult could end up causing cellular apoptosis or survival depending on the severity of the insult and cellular respo...

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Bibliographic Details
Main Authors: Ismail, Norsharina, Ismail, Maznah, Imam, Mustapha Umar, Azmi, Nur Hanisah, Fathy, Siti Farhana, Foo, Jhi Biau, Abu Bakar, Muhammad Firdaus
Format: Article
Language:English
Published: BioMed Central 2014
Online Access:http://psasir.upm.edu.my/id/eprint/34480/1/Mechanistic%20basis%20for%20protection%20of%20differentiated.pdf