Synthesis and SAR study of diarylpentanoid analogues as new anti-inflammatory agents

Synthesis and SAR study of diarylpentanoid analogues as new anti-inflammatory agents

A series of ninety-seven diarylpentanoid derivatives were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using interferone gamma (IFN-γ)/lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Twelve compounds (9, 25, 28, 43, 63, 64, 81, 83, 84, 86, 88...

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Bibliographic Details
Main Authors: Leong, Sze Wei, Mohd Faudzi, Siti Munirah, Abas, Faridah, Mohd Aluwi, Mohd Fadhlizil Fasihi, Rullah, Kamal, Lam, Kok Wai, Abdul Bahari, Mohd Nazri, Ahmad, Syahida, Tham, Chau Ling, Shaari, Khozirah, Lajis, Md. Nordin
Format: Article
Language:English
Published: MDPI 2014
Online Access:http://psasir.upm.edu.my/id/eprint/35571/1/Synthesis%20and%20Sar%20Study%20of%20Diarylpentanoid%20Analogues%20as%20New.pdf

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http://psasir.upm.edu.my/id/eprint/35571/1/Synthesis%20and%20Sar%20Study%20of%20Diarylpentanoid%20Analogues%20as%20New.pdf

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