Transgene expression from CpG-reduced lentiviral gene delivery vectors in vitro
Current viral gene delivery vectors for gene therapy are inefficient due to short-lived transgene expression attributed to the cytosine-phosphate-guanine (CpG) motifs in the transgene. Here we assessed the effects of CpG motif reduction in lentiviral (LV) gene delivery context on the level and durat...
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| Format: | Article |
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Elsevier
2014
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