Zerumbone induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in Jurkat cell line

This investigation determined the anticancer properties of zerumbone (ZER) on the human T-cell (Jurkat) line using the MTT assay, microscopic evaluations, flow cytometric analyses, and caspase activity estimations. The results showed that ZER is selectively cytotoxic to Jurkat cells in a dose and ti...

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Bibliographic Details
Main Authors: Rahman, Heshu Sulaiman, Abdullah, Rasedee, Chartrand, Max Stanley, Othman, Hemn Hassan, Yeap, Swee Keong, Namvar, Farideh
Format: Article
Published: Natural Product 2014