Asymmetric Michael reaction catalyzed by mimicked peptides
Peptides mimicked from active site of promiscuous aldo-ketoreductase were synthesized and tested as asymmetry catalysts in the Michael adduct reaction of aldehydes or ketones with nitroolefins to furnish the corresponding γ-nitroaldehydes, γ-nitroketones with up to 93 % yield, 99:1 dr and 71 % ee at...
Main Authors: | , , , , , |
---|---|
格式: | 文件 |
语言: | English |
出版: |
Springer
2014
|
在线阅读: | http://psasir.upm.edu.my/id/eprint/36591/1/Asymmetric%20Michael%20reaction%20catalyzed%20by%20mimicked%20peptides.pdf |