Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study

Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study

We have synthesized quinoxaline analogs (1–25), characterized by 1H-NMR and HREI-MS and evaluated for thymidine phosphorylase inhibition. Among the series, nineteen analogs showed better inhibition when compared with the standard inhibitor 7-Deazaxanthine (IC50 = 38.68 ± 4.42 µM). The most potent co...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Almandil, Noor Barak, Taha, Muhammad, Farooq, Rai Khalid, Alhibshi, Amani, Ibrahim, Mohamed, Anouar, El Hassane, Gollapalli, Mohammed, Rahim, Fazal, Nawaz, Muhammad, Shah, Syed Adnan Ali, Ahmed, Qamar Uddin, Zakaria, Zainul Amiruddin
বিন্যাস: প্রবন্ধ
ভাষা:English
প্রকাশিত: MDPI 2019
অনলাইন ব্যবহার করুন:http://psasir.upm.edu.my/id/eprint/38421/1/38421.pdf

আন্তর্জাল

http://psasir.upm.edu.my/id/eprint/38421/1/38421.pdf

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