Cofactor strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase

Cofactor strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase

Metabolic reprogramming is a hallmark of cancer cells. Strap (stress-responsive activator of p300) is a novel TPR motif OB-fold protein that contributes to p53 transcriptional activation. We show here that, in addition to its established transcriptional role, Strap is localised at mitochondria where...

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Bibliographic Details
Main Authors: Maniam, Sandra, Coutts, Amanda S., Stratford, Michael R. L., McGouran, Joanna F., Kessler, Benedikit M., La Thangue, N. B.
Format: Article
Language:English
Published: Nature Publishing Group 2015
Online Access:http://psasir.upm.edu.my/id/eprint/44087/1/Cofactor%20strap%20regulates%20oxidative%20phosphorylation%20and%20mitochondrial%20p53%20activity%20through%20ATP%20synthase.pdf

Internet

http://psasir.upm.edu.my/id/eprint/44087/1/Cofactor%20strap%20regulates%20oxidative%20phosphorylation%20and%20mitochondrial%20p53%20activity%20through%20ATP%20synthase.pdf

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