SRS06, a new semisynthetic andrographolide derivative with improved anticancer potency and selectivity, inhibits nuclear factor-kB nuclear binding in the A549 non-small cell lung cancer cell line
Background: Andrographolide has been reported with anticancer and anti-inflammatory properties through the inhibition of the activity of signaling molecules such as v-Src, nuclear factor-κB (NF-κB), STAT3, and PI3K. NF-κB has been proven to promote cancer cell survival, and targeting this pathway wi...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Karger Publishers
2015
|
Online Access: | http://psasir.upm.edu.my/id/eprint/46370/1/SRS06%2C%20a%20new%20semisynthetic%20andrographolide%20derivative%20with%20improved%20anticancer%20potency%20and%20selectivity%2C%20inhibits%20nuclear%20factor-kB%20nuclear%20binding%20in%20the%20A549%20non-small%20cell%20lung%20cancer%20cell%20line.pdf |