The curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one induces apoptosis and downregulates E6 and E7 oncogene expression in HPV16 and HPV18-infected cervical cancer cells

The curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one induces apoptosis and downregulates E6 and E7 oncogene expression in HPV16 and HPV18-infected cervical cancer cells

In an effort to study curcumin analogues as an alternative to improve the therapeutic efficacy of curcumin, we screened the cytotoxic potential of four diarylpentanoids using the HeLa and CaSki cervical cancer cell lines. Determination of their EC50 values indicated relatively higher potency of 1,5-...

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Bibliografske podrobnosti
Main Authors: Paulraj, Felicia, Abas, Faridah, Lajis, Nordin, Othman, Iekhsan, Syed Hassan, Sharifah, Naidu, Rakesh
Format: Article
Jezik:English
Izdano: MDPI 2015
Online dostop:http://psasir.upm.edu.my/id/eprint/46538/1/The%20curcumin%20analogue%201%2C5-bis%282-hydroxyphenyl%29-1%2C4-pentadiene-3-one%20induces%20apoptosis%20and%20downregulates%20E6%20and%20E7%20oncogene%20expression%20in%20HPV16%20and%20HPV18-infected%20cervical%20cancer%20cells.pdf

Internet

http://psasir.upm.edu.my/id/eprint/46538/1/The%20curcumin%20analogue%201%2C5-bis%282-hydroxyphenyl%29-1%2C4-pentadiene-3-one%20induces%20apoptosis%20and%20downregulates%20E6%20and%20E7%20oncogene%20expression%20in%20HPV16%20and%20HPV18-infected%20cervical%20cancer%20cells.pdf

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