The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

The aim of this work is to review current knowledge relating the established cancer hallmark, sustained cell proliferation to the existence of chemicals present as low dose mixtures in the environment. Normal cell proliferation is under tight control, i.e. cells respond to a signal to proliferate, a...

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Main Authors: Engström, Wilhelm, Darbre, Philippa, Eriksson, Staffan, Gulliver, Linda, Hultman, Tove, Karamouzis, Michalis V., Klaunig, James E., Mehta, Rekha, Moorwood, Kim, Sanderson, Thomas, Sone, Hideko, Vadgama, Pankaj, Wagemaker, Gerard, Ward, Andrew, Singh, Neetu, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Colacci, Anna Maria, Vaccari, Monica, Mondello, Chiara, Scovassi, A. Ivana, Raju, Jayadev, Abd. Hamid@ Abd. Razak, Roslida, Memeo, Lorenzo, Forte, Stefano, Roy, Rabindra, Woodrick, Jordan, Salem, Hosni K., Ryan, Elizabeth P., Brown, Dustin G., Bisson, William H.
Format: Article
Language:English
Published: Oxford University Press 2015
Online Access:http://psasir.upm.edu.my/id/eprint/46664/1/The%20potential%20for%20chemical%20mixtures%20from%20the%20environment%20to%20enable%20the%20cancer%20hallmark%20of%20sustained%20proliferative%20signalling.pdf