The use of Taqman genotyping assays for rapid confirmation of B-thalassaemia mutations in the Malays: accurate diagnosis with low DNA concentrations

The use of Taqman genotyping assays for rapid confirmation of B-thalassaemia mutations in the Malays: accurate diagnosis with low DNA concentrations

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Introduction: In Malaysia, β-thalassaemia is a common inherited blood disorder in haemoglobin synthesis with a carrier rate of 4.5%. Currently, PCR-incorporating techniques such as amplification refractory mutation system (ARMS) or reverse dot blot hybridization (RDBH) are used in β-thalassaemia mut...

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Bibliographic Details
Main Authors: Teh, L. K., Lee, T. Y., Tan, Mary Anne Jin Ai, Lai, Mei I., George, E.
Format: Article
Language:English
Published: Wiley-Blackwell Publishing 2015
Online Access:http://psasir.upm.edu.my/id/eprint/46713/1/The%20use%20of%20Taqman%20genotyping%20assays%20for%20rapid%20confirmation%20of%20B-thalassaemia%20mutations%20in%20the%20Malays%3B%20accurate%20diagnosis%20with%20low%20DNA%20concentrations_New.pdf

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http://psasir.upm.edu.my/id/eprint/46713/1/The%20use%20of%20Taqman%20genotyping%20assays%20for%20rapid%20confirmation%20of%20B-thalassaemia%20mutations%20in%20the%20Malays%3B%20accurate%20diagnosis%20with%20low%20DNA%20concentrations_New.pdf

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