Effect of transforming growth factor-β1, insulin-like growth factor-I and insulin-like growth factor-II on cell growth and oestrogen metabolism in human breast cancer cell lines

Oestrogens play an important role in the development of breast cancer. Oestrone sulphate (E1S) acts as a huge reservoir of oestrogens in the breast and is converted to oestrone (E1) by oestrone sulphatase (E1STS). E1 is then reversibly converted to the potent oestrogen, oestradiol (E2) by oestradiol...

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Bibliographic Details
Main Authors: Wong, Shew Fung, Reimann, Karin, Lai, Leslie C.
Format: Article
Language:English
Published: Royal College of Pathologists of Australasia 2001
Online Access:http://psasir.upm.edu.my/id/eprint/50002/1/Effect%20of%20transforming%20growth%20factor-%CE%B21%2C%20insulin-like%20growth%20factor-I%20and%20insulin-like%20growth%20factor-II%20on%20cell%20growth%20and%20oestrogen%20metabolism%20in%20human%20breast%20cancer%20cell%20lines.pdf