The effect of water deprivation on the pharmacokinetics of antipyrine and sulphadimidine following intravenous administration in Nubian goats

The effect of water deprivation on the pharmacokinetic parameters of antipyrine and sulphadimidine in the Nubian goat was studied. Water deprivation, to a level of dehydration at which the animals lost an average of 7.5% body weight, resulted in a significant reduction in antipyrine clearance (p <...

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Bibliographic Details
Main Authors: Elsheikh, Hatim Ali, Osman, I. A. M., Abdullah, A. S.
Format: Article
Language:English
English
Published: Kluwer Academic Publishers 1997
Online Access:http://psasir.upm.edu.my/id/eprint/51050/1/The%20effect%20of%20water%20deprivation%20on%20the%20pharmacokinetics%20of%20antipyrine%20and%20sulphadimidine%20following%20intravenous%20administration%20in%20Nubian%20goats.pdf
http://psasir.upm.edu.my/id/eprint/51050/7/A_1005975016275.pdf