Insulinotropic activity of Tinospora crispa extract: effect on ß-cell Ca2+ handling
The mechanism of insulinotropic action of Tinospora crispa was investigated in vitro using an insulin-secreting clonal β-cell line, HIT-T15. The aqueous extract sensitizes the β-cell to extracellular Ca2+ and promotes intracellular Ca2+ accumulation which in turn causes increased insulin release. Th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
John Wiley & Sons
1998
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| Online Access: | http://psasir.upm.edu.my/id/eprint/51742/1/51742.pdf |