Modulation of hydrogen peroxide-induced oxidative stress in human neuronal cells by Thymoquinone-rich fraction and Thymoquinone via transcriptomic regulation of antioxidant and apoptotic signaling genes

Modulation of hydrogen peroxide-induced oxidative stress in human neuronal cells by Thymoquinone-rich fraction and Thymoquinone via transcriptomic regulation of antioxidant and apoptotic signaling genes

Nigella sativa Linn. (N. sativa) and its bioactive constituent Thymoquinone (TQ) have demonstrated numerous pharmacological attributes. In the present study, the neuroprotective properties of Thymoquinone-rich fraction (TQRF) and TQ against hydrogen peroxide- (H2O2-) induced neurotoxicity in differe...

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Bibliographic Details
Main Authors: Ismail, Norsharina, Ismail, Maznah, Azmi, Nur Hanisah, Abu Bakar, Muhammad Firdaus, Basri, Hamidon, Abdullah, Maizaton Atmadini
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:http://psasir.upm.edu.my/id/eprint/53316/1/Modulation%20of%20hydrogen%20peroxide-induced%20oxidative%20stress.pdf

Internet

http://psasir.upm.edu.my/id/eprint/53316/1/Modulation%20of%20hydrogen%20peroxide-induced%20oxidative%20stress.pdf

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