Newcastle disease virus degrades HIF-1a through proteasomal pathways independent of VHL and p53
Newcastle disease virus (NDV) is a candidate agent for oncolytic virotherapy. Despite its potential, the exact mechanism of its oncolysis is still not known. Recently, we reported that NDV exhibited an increased oncolytic activity in hypoxic cancer cells. These types of cells negatively affect thera...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Microbiology Society
2016
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/53381/1/Newcastle%20disease%20virus%20degrades%20HIF-1%CE%B1%20through%20proteasomal%20pathways%20independent%20of%20VHL%20and%20p53.pdf |