Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF-κB and IL-6/STAT3 as potential targets

Ulcerative colitis (UC) is a nonspecific inflammatory disorder characterized by oxidative and nitrosative stress, leucocyte infiltration, and upregulation of inflammatory mediators. Boldine is an alkaloid compound found in Boldo tree, with multiple pharmacological actions, mainly anti-inflammatory,...

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Bibliographic Details
Main Authors: Pandurangan, Ashok Kumar, Mohebali, Nooshin, Hasanpourghadi, Mohadeseh, Chung, Yeng Looi, Mustafa, Mohammad Rais, Mohd Esa, Norhaizan
Format: Article
Language:English
Published: Wiley-Blackwell Publishing 2016
Online Access:http://psasir.upm.edu.my/id/eprint/55218/1/article.pdf