2, 4, 6,-trihydroxy- 3-geranylacetophenone (tHGA) inhibits newly synthesized mediators release in IgE-mediated mast cell degranulation

Mast cells are important effector cells of the innate immune system and participate in allergy reaction. Upon FCERI aggregation, mast cells secrete preformed mediators such as histamine as well as newly synthesized mediators including prostaglandins, leukotrienes and proinflammatory cytokines. Our p...

Full description

Bibliographic Details
Main Authors: Tan, Ji Wei, Israf Ali, Daud Ahmad, Shaari, Khozirah, Tham, Chau Ling
Format: Article
Language:English
Published: Microscopy Society Malaysia 2015
Online Access:http://psasir.upm.edu.my/id/eprint/57687/1/2%2C%204%2C%206%2C-trihydroxy-%203-geranylacetophenone%20%28tHGA%29%20inhibits%20newly%20synthesized%20mediators%20release%20in%20IgE-mediated%20mast%20cell%20degranulation.pdf