Integrated strategy for the assessment of kidney toxicity: the case of aristolochic acids

This PhD thesis aimed to provide additional evidence to demonstrate the potential of an integrated testing strategy using in vitro assays with physiologically based kinetic (PBK) modeling based-reverse dosimetry to predict in vivo toxicity without animal testing. Kidney toxicity was chosen as the to...

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Bibliographic Details
Main Author: Abdullah, Rozaini
Format: Book
Language:English
Published: Wageningen University 2017
Online Access:http://psasir.upm.edu.my/id/eprint/61346/1/Integrated%20strategy%20for%20the%20assessment%20of%20kidney%20toxicity%3B%20the%20case%20of%20aristolochic%20acids.pdf