Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells

Aims: Curcumin is a lead compound of the rhizomes of Curcuma longa and possess a broad range of pharmacological activities. Chemically, curcumin is 1,3-dicarbonyl class of compound, which exhibits keto-enol tautomerism. Despite of its strong biological properties, curcumin has yet been recommended a...

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Main Authors: Mohd Ali, Norlaily, Swee, Keong Yeap, Abu, Nadiah, Kian, Lam Lim, Ky, Huynh, Pauzi, Ahmad Zaim Mat, Wan, Yong Ho, Sheau, Wei Tan, Alan‑Ong, Han Kiat, Zareen, Seema, Alitheen, Noorjahan Banu, Akhtar, M. Nadeem
Format: Article
Language:English
Published: BioMed Central 2017
Online Access:http://psasir.upm.edu.my/id/eprint/63373/1/Synthetic%20curcumin%20derivative%20DK1%20possessed%20G2M%20arrest%20and%20induced%20apoptosis%20through%20accumulation%20of%20intracellular%20ROS%20in%20MCF-7%20breast%20cancer%20cells.pdf