Zebrafish phenotypic screen identifies novel Notch antagonists

Zebrafish represents a powerful in vivo model for phenotype-based drug discovery to identify clinically relevant small molecules. By utilizing this model, we evaluated natural product derived compounds that could potentially modulate Notch signaling that is important in both zebrafish embryogenesis...

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Bibliographic Details
Main Authors: Velaithan, Vithya, Okuda, Kazuhide Shaun, Mei, Fong Ng, Samat, Norazwana, Sze, Wei Leong, Faudzi, Siti Munirah Mohd, Abas, Faridah, Shaari, Khozirah, Sok, Ching Cheong, Pei, Jean Tan, Patel, Vyomesh
Format: Article
Language:English
Published: Springer 2017
Online Access:http://psasir.upm.edu.my/id/eprint/63740/1/Zebrafish%20phenotypic%20screen%20identifies%20novel%20Notch%20antagonists.pdf