Evaluation of curcumin derivatives as new cyclooxygenase-2 inhibitors via in silico and in vitro analyses
Prostaglandin E2 (PGE2) is one of the lipid mediators of inflammation. Chronic inflammation drives overproduction of PGE2 that leads to development of chronic inflammatory diseases. PGE2 is synthesized by cyclooxygenase (COX) enzyme that exists in isoforms of COX-1, which is constitutively expressed...
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| Format: | Thesis |
| Language: | English |
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2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/68964/1/FBSB%202016%207%20-%20IR.pdf |