Screening, design, synthesis and bioactivity of inhibitors against Protein Arginine Deiminase type IV

Protein Arginine Deiminase IV (PAD4) is a new target for rheumatoid arthritis (RA) therapeutic. It catalyses the citrullination process in human body that produces citrullinated protein which is believed to be the root cause of RA. Inhibitor for the enzyme can be a drug for the treatment of RA. The...

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Bibliographic Details
Main Author: Teo, Chian Ying
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/71185/1/FS%202015%2072%20IR.pdf