Design, synthesis and docking studies of Flavokawain B type chalcones and their cytotoxic effects on MCF-7 and MDA-MB-231 cell lines
Flavokawain B (1) is a natural chalcone extracted from the roots of Piper methysticum, and has been proven to be a potential cytotoxic compound. Using the partial structure of flavokawain B (FKB), about 23 analogs have been synthesized. Among them, compounds 8, 13 and 23 were found in new FKB deriva...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/72197/1/Design%2C%20synthesis%20and%20docking%20studies%20.pdf |