Identification of α-glucosidase inhibitorsfrom Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking

The present study used in vitro and in silico techniques, as well as the metabolomics approach to characterise α-glucosidase inhibitors from different fractions of Clinacanthus nutans. C. nutans is a medicinal plant belonging to the Acanthaceae family, and is traditionally used to treat diabetes in...

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Main Authors: Murugesu, Suganya, Ibrahim, Zalikha, Ahmed, Qamar Uddin, Uzir, Bisha Fathamah, Nik Yusoff, Nik Idris, Perumal, Vikneswari, Abas, Faridah, Shaari, Khozirah, Khatib, Alfi
Format: Article
Language:English
Published: Xi'an Jiaotong University 2019
Online Access:http://psasir.upm.edu.my/id/eprint/80140/1/Identification%20of%20%CE%B1-glucosidase%20inhibitorsfrom%20Clinacanthus%20nutans%20leaf%20extract%20using%20liquid%20chromatography-mass%20spectrometry-based%20metabolomics%20and%20protein-ligand%20interaction%20with%20molecular%20docking.pdf