An inhibited dopamine synthesizing cell model of AADC deficiency

Introduction: Aromatic L-amino acid decarboxylase deficiency (AADC) is a rare autosomal recessive pediatric neurotransmitter disease. To date it remains poorly understood mainly due to an absence of a disease model. The dopaminergic neuroblastoma cell SH-SY5Y was chosen to develop our AADC deficienc...

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Bibliographic Details
Main Authors: Khalid, Melati, Mohd Moklas, Mohamad Aris
Format: Article
Language:English
Published: Biome Scientia 2019
Online Access:http://psasir.upm.edu.my/id/eprint/80606/1/AADC.pdf