Optimization of nanoemulsion containing gemcitabine and evaluation of its cytotoxicity towards human fetal lung fibroblast (MRC5) and human lung carcinoma (A549) cells

Background: Gemcitabine (GEM) is a chemotherapeutic agent, which is known to battle cancer but challenging due to its hydrophilic nature. Nanoemulsion is water-in-oil (W/O) nanoemulsion shows potential as a carrier system in delivering gemcitabine to the cancer cell. Methods: The behaviour of GEM i...

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Bibliographic Details
Main Authors: Wahgiman, Nadiatul Atiqah, Salim, Norazlinaliza, Abdul Rahman, Mohd Basyaruddin, Ashari, Siti Efliza
Format: Article
Language:English
Published: Dove Medical Press 2019
Online Access:http://psasir.upm.edu.my/id/eprint/81571/1/GEM.pdf