REST and neural gene network Dysregulation in iPSC models of Alzheimer’s disease

REST and neural gene network Dysregulation in iPSC models of Alzheimer’s disease

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The molecular basis of the earliest neuronal changes that lead to Alzheimer’s disease (AD) is unclear. Here, we analyze neural cells derived from sporadic AD (SAD), APOE4 gene-edited and control induced pluripotent stem cells (iPSCs). We observe major differences in iPSC-derived neural progenitor (N...

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Príomhchruthaitheoirí: Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan Ta, Su, Susan C., Church, George M., Tsai, Li Huei, Yankner, Bruce A.
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Cell Press 2019
Rochtain ar líne:http://psasir.upm.edu.my/id/eprint/82010/1/REST%20and%20neural%20gene%20network%20.pdf

Ar líne

http://psasir.upm.edu.my/id/eprint/82010/1/REST%20and%20neural%20gene%20network%20.pdf

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