Biochemical and molecular aspects of 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis: a review

1,2-dimethylhydrazine (DMH) is a member in the class of hydrazines, strong DNA alkylating agent, naturally present in cycads. DMH is widely used as a carcinogen to induce colon cancer in animal models. Exploration of DMH-induced colon carcinogenesis in rodent models provides the knowledge to perceiv...

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Bibliographic Details
Main Authors: Venkatachalam, Karthikkumar, Vinayagam, Ramachandran, Anand, Mariadoss Arokia Vijaya, Mat Isa, Nurulfiza, Ponnaiyan, Rajasekar
Format: Article
Language:English
Published: Royal Society of Chemistry 2020
Online Access:http://psasir.upm.edu.my/id/eprint/88023/1/ABSTRACT.pdf