Synthesis and biological evaluation of a series of analogues of 2,4,6-trihydroxy-3-geranylacetophenone, an anti-inflammatory natural product compound
The natural product molecule 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) isolated from the medicinal plant Melicope ptelefolia was shown to exhibit potent lipoxygenase (LOX) inhibitory activity. It is known that LOX plays an important role in inflammatory response as it catalyzes the oxidation of...
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| Format: | Thesis |
| Language: | English |
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2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/92467/1/IB%202017%208%20UPMIR.pdf |