Synthesis and characterization of chitosan-based nanodelivery systems to enhance the anticancer effect of Sorafenib drug in Hepatocellular Carcinoma and Colorectal Adenocarcinoma cell lines

The formation of two nanodelivery systems, Sorafenib (SF)-loaded chitosan (SF-CS) and their folate-coated (SF-CS-FA) nanoparticles (NPs), were developed to enhance SF drug delivery on human Hepatocellular Carcinoma (HepG2) and Colorectal Adenocarcinoma (HT29) cell lines. The ionic gelation method wa...

Full description

Bibliographic Details
Main Authors: Ruman, Umme, Buskaran, Kalaivani, Pastorin, Giorgia, Masarudin, Mas Jaffri, Fakurazi, Sharida, Hussein, Mohd Zobir
Format: Article
Published: MDPI AG 2021