Synthesis of small molecules targeting paclitaxel-induced MyD88 expression in triple-negative breast cancer cell lines

Acquired paclitaxel (PTX) chemoresistance in triple-negative breast cancer (TNBC) can be inferred from the overexpression of toll-like receptor 4 (TLR4) and myeloid differentiation primary response 88 (MyD88) proteins and the activation of the TLR4/MyD88 cascading signalling pathway. Finding a new i...

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Bibliographic Details
Main Authors: Khor, Poh Yen, Stanslas, Johnson, Zhang, Tianshu, Li, Hongyuan, Wang, Xiaohui, Chan, Kok Meng, Lam, Kok Wai
Format: Article
Published: Elsevier 2021